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Perineurial fibroblasts are of mesenchymal origin and form the perineurium. The perineurium plays an important role in maintaining the integrity of the internal peripheral nerve environment by creating a physical barrier that, under physiologic condition, limits the entry of biologically active proteins, infectious agents, and blood-borne cells into the nerve bundles. The perineurial fibroblasts are characterized by distinct ultrastructural features, including non-branching thin cytoplasmic processes coated by an external lamina and joined at their ends by a tight junction, few organelles, actin and vimentin filaments, and numerous pinocytotic vesicles. Perineurial fibroblasts are initially recruited from the surrounding mesenchyme to form a loose, permeable sheath around axons and Schwann cells, where they are separated by the extracellular matrix. These cells later undergo a mesenchymal-to-epithelial transition to form tight junctions and organize into the perineurium. Perineurial fibroblasts are immunoreactive for vimentin and epithelial membrane antigen but not for the Schwann cell marker S-100.
MPNF from ScienCell Research Laboratories are isolated from postnatal day 8 CD-1 mouse nerve. MPNF are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. MPNF are characterized by immunofluorescence with antibodies specific to vimentin and/or fibronectin. MPNF are negative for mycoplasma, bacteria, yeast, and fungi. MPNF are guaranteed to further expand for 5 population doublings under the conditions provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Fibroblast Medium (FM, Cat. #2301) for culturing MPNF in vitro.
货号 | M1710 |
产地 | 北美 |
缩写 | MPNF |
规格 | 5 x 10^5 cells/vial |
用途 | 科研 |
储存 | 液氮 |
运输 | 干冰 |
小鼠细胞系统
小鼠细胞系统
货号 | 产品名称 | 规格 | 价格 | 指令 | |
M4200 | 小鼠肾系膜细胞 | 5 x 10^5 cells/vial | $446 | + | |
M4200-57 | 小鼠肾系膜细胞 | 5 x 10^5 cells/vial | $470 | + | |
M5300 | 小鼠肝星状细胞 | 5 x 10^5 cells/vial | $477 | + | |
M5300-57 | 小鼠肝星状细胞 | 5 x 10^5 cells/vial | $544 | + | |
M5340 | 小鼠肝巨噬细胞 | 1 x 10^6 cells/vial | $372 | + | |
M5340-57 | 小鼠肝巨噬细胞 | 1 x 10^6 cells/vial | $417 | + | |
M5540 | 小鼠脾细胞 | 10 x 10^6 cells/vial | $198 | + | |
M5540-25 | 小鼠脾细胞 | 25 x 10^6 cells/vial | $390 | + | |
M5540-57 | 小鼠脾细胞 | 10 x 10^6 cells/vial | $238 | + | |
M5550 | 小鼠脾脏巨噬细胞 | 1 x 10^6 cells/vial | $372 | + | |
M5550-57 | 小鼠脾脏巨噬细胞 | 1 x 10^6 cells/vial | $417 | + | |
M6200 | 小鼠心肌细胞 | 1 x 10^6 cells/vial | $446 | + | |
M6200-57 | 小鼠心肌细胞 | 1 x 10^6 cells/vial | $489 | + | |
M6300 | 小鼠心脏成纤维细胞 | 5 x 10^5 cells/vial | $446 | + | |
M6300-57 | 小鼠心脏成纤维细胞 | 5 x 10^5 cells/vial | $489 | + | |
M7540 | 小鼠胚胎成纤维细胞 | 1 x 10^6 cells/vial | $143 | + | |
M7540-2-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial | $44 | + | |
M7540-2-mt-v10 | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial. 10 vials/pk | $381 | + | |
M7540-2-mt-v20 | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial. 20 vials/pk | $777 | + | |
M7540-2-mt-v5 | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial. 5 vials/pk | $201 | + | |
M7540-5 | 小鼠胚胎成纤维细胞 | 5 x 10^6 cells/vial | $278 | + | |
M7540-5-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 5 x 10^6 cells/vial | $102 | + | |
M7540-57 | 小鼠胚胎成纤维细胞 | 5 x 10^6 cells/vial | $327 | + | |
M7540-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 1 x 10^6 cells/vial | $28 | + | |
M7570 | 小鼠胚胎成纤维细胞 | 1 x 10^6 cells/vial | $143 | + | |
M7570-5 | 小鼠胚胎成纤维细胞 | 5 x 10^6 cells/vial | $283 | + | |
M7570-5-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 5 x 10^6 cells/vial | $105 | + | |
M7570-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 1 x 10^6 cells/vial | $25 | + |