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人类精神分裂症qPCR检测试剂盒

英文名:Human Schizophrenia qPCR Array Kit

货号:GK075

价格:$250

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ScienCell's GeneQuery™ Human Schizophrenia qPCR Array Kit (GQH-SCZ) profiles 88 key genes involved in the development and progression of schizophrenia.  Schizophrenia is a chronic mental disorder characterized by altered mood, thought, and behavior.  Both environmental and genetic factors contribute to the risks of developing schizophrenia and the symptoms can be be debilitating.  Current treatments mainly focus on relieving symptoms because the exact underlying mechanisms causing schizophrenia are still unknown.  Below are brief examples of how included genes may be grouped according to their significance:

  • Susceptibility: GRM3, DISC1, DAOA, RGS4, NRG1
  • Early onset schizophrenia: DRD3, HTR3A, NDUFS4, SOX10, BDNF
  • Paranoid schizophrenia: HTR2A, COMT, PRL, MAOA, CCKAR

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis. 

 GeneQuery™ Human Schizophrenia qPCR Array Plate Layout* (8 controls in Bold and Italic)

 

1

2

3

4

5

6

7

8

9

10

11

12

A

AKT1

CD40LG

DBH

DRD5

GAD1

GRIN2A

HTR2C

NDUFS4

PDE4B

SETD1A

TAAR6

β-actin

B

APOL2

CHN2

DISC1

DTNBP1

GNAL

GRIN2B

HTR3A

NOS1

PPP1R1B

SLC1A1

TH

GAPDH

C

APOL4

CHRM1

DISC2

ECSCR

GRIA1

GRM1

INS

NOTCH4

PPP3CC

SLC6A3

TNF

LDHA

D

ARVCF

CHRNA7

DNMT3B

ERBB4

GRIA4

GRM3

KCNN3

NPAS3

PRL

SLC6A4

TPH1

NONO

E

BDNF

CLINT1

DRD1

FOLH1

GRIK1

HSPA1B

LRRTM1

NRG1

QK1

SOX10

TPH2

PPIH

F

CACNG2

COMT

DRD2

FZD3

GRIK3

HSPA1L

MAOA

NRG3

RELN

SULT4A1

YWHAH

GDC

G

CALB1

CYP2D6

DRD3

GABBR1

GRIK4

HTR1A

MC4R

NTF3

RGS4

SYN2

ZDHHC8

PPC

H

CCKAR

DAOA

DRD4

GABRB1

GRIN1

HTR2A

MTHFR

NTS

RTN4R

SYN3

ZNF804A

NTC 

 * gene selection may be updated based on new research and development

货号GK075
产地美国
缩写GQH-SCZ
规格One 96-well plate, one 20ul reaction per well
用途科研
储存4°C
运输胶冰
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