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人类帕金森病qPCR检测试剂盒

英文名:Human Parkinson’s Disease qPCR Array Kit

货号:GK058

价格:$250

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ScienCell's GeneQuery™ Human Parkinson’s Disease qPCR Array Kit (GQH-PKD) profiles 88 key genes involved in the development and progression of Parkinson’s disease.  Parkinson’s disease is a progressive nervous system disorder characterized by motor skill impairment.  Symptoms can be categorized in four primary categories: tremors, rigidity, bradykinesia, and impaired balance.  There are currently no laboratory tests to help diagnose Parkinson’s disease or treatments to cure it, however a variety of medications exist to allay symptoms.  Below are brief examples of how included genes may be grouped according to their significance:

  • Susceptibility: PARK2, PINK1, LRRK2, GSTT1, FTL
  • Early onset Parkinson’s: FBXO7, PACRG, PARK7, UCHL1, VPS13C
  • Neurotransmission: DRD1, GRM1, MAOB, MAP2, SLC6A3
  • CNS Development: CHAT, GDNF, NGF, NRTN, PSPN
  • Metabolism: ADH1C, COMT, HMOX1, NOS1, NQO1

GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis. 

GeneQuery™ Human Parkinson’s Disease qPCR Array Plate Layout* (8 controls in Bold and Italic)

 

1

2

3

4

5

6

7

8

9

10

11

12

A

ADH1C

CALB1

CP

DRD4

GLUD2

HMOX1

MAOB

NNMT

PARK7

SLC18A2

SPR

β-actin

B

ADORA2A

CASP3

CYCS

FBXO7

GPR37

HTR1A

MAP2

NOS1

PDYN

SLC6A3

STH

GAPDH

C

AKT1

CAT

CYP2D6

FGF20

GPX1

HTT

MAPK8

NQO1

PINK1

SLC6A4

TAC1

LDHA

D

APOE

CDK5

DBH

FGF8

GRM1

IREB2

MAPT

NR4A2

PITX3

SNCA

TBP

NONO

E

APP

CHAT

DNAJC13

FTL

GRM5

LMX1B

MSX1

NRTN

PSPN

SNCAIP

TH

PPIH

F

ATXN2

CHM

DRD1

GAD1

GSTO1

LRRK1

NAT2

NTS

RNF19A

SNCB

UCHL1

GDC

G

ATXN3

CNR1

DRD2

GCH1

GSTO2

LRRK2

NDUFS4

PACRG

RPS27A

SOD1

VPS13C

PPC

H

BDNF

COMT

DRD3

GDNF

GSTT1

MAOA

NGF

PARK2

SIAH1

SOD2

VPS35

NTC

  * gene selection may be updated based on new research and development

货号GK058
产地美国
缩写GQH-PKD
规格One 96-well plate, one 20ul reaction per well
用途科研
储存4°C
运输胶冰
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