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人骨髓间充质干细胞 HMSC-bm

英文名:Human Bone Marrow-derived Mesenchymal Stem Cells

货号:7500

价格:$682

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间充质干细胞是特征明确的一类成人干细胞。它们有发育为成熟细胞的潜在能力而产生脂肪、软骨、骨骼和肌肉。这些特性与它们发育中的可塑性共同作用,使人们对用间充质干细胞来替换受损组织的潜在能力产生了极大的兴趣。间充质干细胞无血清培养,在转化生长因子作用下会分化成软骨细胞。相反,在有血清、抗坏血酸和地塞米松的作用下会分化成成骨细胞。间充质干细胞有能力更新和分化成多种间充质组织。间充质干细胞有潜能被移植到受损伤的部位或者种植到仿生支架上,生长形成适当的组织结构。
Sciencell研究实验室的人骨髓间充质干细胞是从人骨髓组织中分离得到的,原代冻存,冰冻运输。每管细胞密度超过5×10^5/ml。人骨髓间充质干细胞经免疫荧光鉴定、和CD73,CD90,CD105的抗体鉴定,以及分化后的脂质染色鉴定。本细胞经检测不含HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌。如采用ScienCell 实验室特制的培养基,可保证此细胞15倍增。

推荐培养基:间充质干细胞培养基 (MSCM, Cat. #7501)

货号7500
产地美国
缩写HMSC-ad
规格5 x 10^5 /1ml
用途科研
储存液氮
运输干冰
1.) Lee HK, Finniss S, Cazacu S, Bucris E, Ziv-Av A, Xiang C, Bobbitt K, Rempel SA, Hasselbach L, Mikkelsen T, Slavin S, Brodie C. (2013) "Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal."?Oncotarget. 4: 346-61.

2.) Lu L, Song HF, Zhang WG, Liu XQ, Zhu Q, Cheng XL, Yang GJ, Li A, Xiao ZC. (2012) "Potential role of 20S proteasome in maintaining stem cell integrity of human bone marrow stromal cells in prolonged culture expansion."?Biochem Biophys Res Commun. 422: 121-7.

3.) Robin TP, Smith A, McKinsey E, Reaves L, Jedlicka P, Ford HL. (2012) "EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance."?Mol Cancer Res. 10: 1098-108.?

4.) Suh N, Paul S, Lee HJ, Yoon T, Shah N, Son AI, Reddi AH, Medici D, Sporn MB. (2012) "Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis."?Osteoarthritis Cartilage. 20: 446-50.

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6.) Dissanayaka WL, Zhu X, Zhang C, Jin L. (2011) "Characterization of dental pulp stem cells isolated from canine premolars."?J Endod. 37: 1074-80.

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8.) Liu Y, Xu X, Ma X, Martin-Rendon E, Watt S, Cui Z. (2010) "Cryopreservation of human bone marrow-derived mesenchymal stem cells with reduced dimethylsulfoxide and well-defined freezing solutions."?Biotechnol Prog. 26: 1635-43.

9.) Chadipiralla K, Yochim JM, Bahuleyan B, Huang CY, Garcia-Godoy F, Murray PE, Stelnicki EJ. (2010) "Osteogenic differentiation of stem cells derived from human periodontal ligaments and pulp of human exfoliated deciduous teeth."?Cell Tissue Res. 340: 323-33.

10.) Li GC, Ye QH, Xue YH, Sun HJ, Zhou HJ, Ren N, Jia HL, Shi J, Wu JC, Dai C, Dong QZ, Qin LX. (2010) "Human mesenchymal stem cells inhibit metastasis of a hepatocellular carcinoma model using the MHCC97-H cell line."?Cancer Sci. 101: 2546-53.

11.) Li M, Jayandharan GR, Li B, Ling C, Ma W, Srivastava A, Zhong L. (2010) "High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy."?Hum Gene Ther. 21: 1527-43.

12.) Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR. (2010) "Conversion of vascular endothelial cells into multipotent stem-like cells."?Nat Med. 16: 1400-6.

 
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